Kalokerinos was a general practitioner (MD) at a remote Australian public hospital/clinic where many of the patients were aboriginal children with life-threatening and often life-ending diseases that "white" children rarely got. This situation was greatly improved by the administration of modest amounts of vitamin C.
Irwin Stone asserted that humans require much larger amounts of Vitamin C for optimal health than is necessary to prevent scurvy. He introduced Linus Pauling to Vitamin C and is recognised within orthomolecular medicine as one of its founders.